What causes the formation of COVID-19 variants? The use of antiviral drugs The use of COVID-19 vaccines Random mutations during viral replications There is current no scientific explanation on how the variants form

The formation of COVID-19 variants is primarily caused by **random mutations during viral replications**. Here's a brief explanation of the other options: 1. **The use of antiviral drugs**: While antiviral drugs can influence the viral population, they do not directly cause the formation of variants. Instead, they may select for resistant strains if the virus mutates in a way that allows it to survive despite the presence of the drug. 2. **The use of COVID-19 vaccines**: Vaccines can lead to the emergence of variants if the virus mutates in response to the immune pressure exerted by the vaccine. However, the primary mechanism for variant formation is still random mutations during replication. 3. **There is currently no scientific explanation on how the variants form**: This statement is incorrect. There is a well-established scientific understanding that variants arise due to mutations that occur when the virus replicates. In summary, the correct answer is that COVID-19 variants are primarily caused by random mutations during viral replications.