A sequence of DNA reads ACTGAGTCA. The next base would have to be any of those four bases. G. A. T. C.
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Bonus Knowledge
In the world of DNA, the sequence you provided can pair with its complementary base, but the next base is determined by the context or function of the DNA. If we're talking about standard DNA replication, it doesn’t strictly follow any specific base; it can indeed be A, T, C, or G, depending on what's needed in that particular moment of cellular activity! For example, if you're looking at protein coding, the next base could contribute to the formation of a new amino acid. Start thinking about which base will best suit the grander scheme of gene expression! The next base could essentially alter the outcome in a deliciously unpredictable way. Happy sequencing!