Answer
**Cell Cycle and Cell Types:**
- **Interphase:**
- **G₁:** Cell growth and normal functions.
- **S:** DNA replication.
- **G₂:** Further growth and preparation for division.
- **Mitosis (M phase):**
- **Prophase:** Chromosomes condense, nuclear membrane breaks down, spindle forms.
- **Metaphase:** Chromosomes align at the center.
- **Anaphase:** Sister chromatids separate.
- **Telophase:** Chromosomes de-condense, nuclear envelope reforms, cytokinesis occurs.
- **Diploid Cells (\(2n\)):**
Cells with two complete sets of chromosomes (e.g., humans have 46).
- **Haploid Cells (\(n\)):**
Cells with one complete set of chromosomes (e.g., humans have 23).
- **Somatic Cells:**
Body cells that are diploid (\(2n\)).
- **Germ Cells/Gametes:**
Reproductive cells that are haploid (\(n\)) and fuse during fertilization to form a diploid zygote.
**Stages of Mitosis:**
1. **Prophase:**
- Chromosomes condense.
- Nuclear envelope breaks down.
- Spindle fibers form.
2. **Metaphase:**
- Chromosomes align at the cell center.
- Spindle fibers attach to kinetochores.
3. **Anaphase:**
- Sister chromatids separate.
- Move to opposite poles.
4. **Telophase:**
- Chromosomes de-condense.
- Nuclear envelope reforms.
- Cytokinesis begins.
**Meiosis:**
- **Meiosis I:**
- **Prophase I:** Chromosomes pair and cross-over.
- **Metaphase I:** Homologous pairs align.
- **Anaphase I:** Homologous chromosomes separate.
- **Telophase I and Cytokinesis:** Two haploid cells formed.
- **Meiosis II:**
- Similar to mitosis, sister chromatids separate.
- Results in four haploid cells.
**Differences Between Mitosis and Meiosis:**
- **Purpose:**
- **Mitosis:** Growth, repair, asexual reproduction.
- **Meiosis:** Sexual reproduction, producing gametes.
- **Number of Divisions:**
- **Mitosis:** One division.
- **Meiosis:** Two divisions.
- **Chromosome Number:**
- **Mitosis:** Daughter cells are diploid.
- **Meiosis:** Daughter cells are haploid.
- **Genetic Variation:**
- **Mitosis:** No variation; identical to parent.
- **Meiosis:** Introduces genetic diversity through crossing-over.
- **Occurrence:**
- **Mitosis:** In somatic cells.
- **Meiosis:** In germ cells.
**Summary:**
- **Interphase** involves growth and DNA replication, leading to **Mitosis**, which divides a diploid cell into two identical diploid daughter cells.
- **Meiosis** is a specialized form of cell division that reduces the chromosome number by half, producing four genetically diverse haploid gametes essential for sexual reproduction.
Solution
### 6. Diagram and List Events of the Cell Cycle
**Diagram of the Cell Cycle:**
```
+-------------------------------------------------------------+
| Interphase |
| (G₁ phase -> S phase -> G₂ phase) |
+-------------------------------------------------------------+
↓
Mitosis (M phase)
+-------------------------------------------------------------+
| Prophase → Metaphase → Anaphase → Telophase (+ Cytokinesis)|
+-------------------------------------------------------------+
```
**Events:**
- **Interphase:**
- **G₁ phase:** Cell growth and normal metabolic functions.
- **S phase:** DNA replication where the genetic material is duplicated.
- **G₂ phase:** Further cell growth and preparation for division.
- **Mitosis (M phase):**
- **Prophase:** Chromosomes condense, the nuclear membrane begins to disintegrate, and the spindle apparatus forms.
- **Metaphase:** Chromosomes line up along the metaphase plate (equatorial plane).
- **Anaphase:** Sister chromatids separate and move toward opposite poles of the cell.
- **Telophase:** Chromosomes de-condense, the nuclear envelope re-forms, and the cell begins to split.
- **Cytokinesis:** Division of the cytoplasm, resulting in two daughter cells.
### 7. Describe Haploid, Diploid, Somatic Cells, Germ Cells/Gametes
- **Diploid Cells (\(2n\)):**
Cells containing two complete sets of chromosomes. In humans, the diploid number is \(46\).
- **Haploid Cells (\(n\)):**
Cells containing one complete set of chromosomes. In humans, the haploid number is \(23\).
- **Somatic Cells:**
These are body cells (e.g., skin, muscle, liver) and are diploid (\(2n\)).
- **Germ Cells/Gametes:**
Reproductive cells (e.g., sperm and egg) that are haploid (\(n\)). They fuse during fertilization to re-establish the diploid number in the zygote.
### 8. Visually Identify the Stages of Mitosis in a Cell
- **Prophase:**
- Chromosomes condense and become visible as distinct structures.
- The nuclear envelope begins to break down.
- The mitotic spindle starts to form.
- **Metaphase:**
- Chromosomes align along the metaphase plate (center of the cell) with their kinetochores attached to spindle fibers coming from opposite poles.
- **Anaphase:**
- Sister chromatids separate and are pulled toward opposite poles of the cell.
- **Telophase:**
- Chromatids reach the poles and begin to de-condense.
- Nuclear envelopes re-form around each set of chromosomes, signaling the near completion of cell division.
- Cytokinesis usually follows, splitting the cell into two daughter cells.
### 9. Determine How the Process of Meiosis Works
**Meiosis** is a two-stage division process that produces four genetically distinct haploid cells. It is critical for sexual reproduction. The stages are divided into two parts: Meiosis I and Meiosis II.
- **Meiosis I (Reductional Division):**
- **Prophase I:** Homologous chromosomes pair up and undergo crossing-over (exchange of genetic material), leading to genetic recombination.
- **Metaphase I:** Paired homologous chromosomes line up at the metaphase plate.
- **Anaphase I:** Homologous chromosomes (each still composed of two sister chromatids) are separated and pulled to opposite poles.
- **Telophase I and Cytokinesis:** Two daughter cells are formed, each with half the number of chromosomes (\(n\)) but each chromosome still consists of two sister chromatids.
- **Meiosis II (Equational Division):**
- Resembles mitosis, where the sister chromatids of each chromosome separate.
- **Prophase II, Metaphase II, Anaphase II, Telophase II:** The sister chromatids are divided, resulting in four genetically distinct haploid cells.
### 10. Differentiate Between Mitosis and Meiosis
- **Purpose:**
- **Mitosis:** Produces two identical daughter cells for growth, repair, and asexual reproduction.
- **Meiosis:** Produces four genetically diverse gametes for sexual reproduction.
- **Number of Divisions:**
- **Mitosis:** One division cycle producing two daughter cells.
- **Meiosis:** Two successive division cycles (Meiosis I and II) producing four daughter cells.
- **Chromosome Number:**
- **Mitosis:** Daughter cells are diploid (\(2n\)) in organisms that are normally diploid.
- **Meiosis:** Daughter cells are haploid (\(n\)); essential for maintaining the chromosome number after fertilization in sexually reproducing organisms.
- **Genetic Variation:**
- **Mitosis:** No crossing-over occurs; daughter cells are genetically identical to the parent cell.
- **Meiosis:** Crossing-over during Prophase I introduces genetic variation among gametes.
- **Occurrence:**
- **Mitosis:** Occurs in somatic cells.
- **Meiosis:** Occurs in germ cells.
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