A mutation causes a sequence of DNA that has the nucleotides TTG to be changed to TCG. The resulting protein has a different sequence of amino acids. Which type of mutation is this? missense nonsense silent frameshift
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This mutation is known as a missense mutation. In missense mutations, a single nucleotide change results in the substitution of one amino acid for another in the protein sequence, which can potentially alter the protein’s function. In your example, the change from TTG to TCG leads to a different amino acid being produced, demonstrating the impact of such a mutation. Missense mutations can have varying effects on protein function; sometimes they can be harmless, while other times they can lead to diseases. A classic example of this is the mutation that causes sickle cell anemia, where a single nucleotide change leads to the production of an abnormal hemoglobin protein. Understanding these mutations is crucial for insights into genetic disorders and developing targeted therapies!