Subtract the following giving your answer in its lowest term. \[ \frac{1-6}{216} \]

To solve the subtraction \( \frac{1-6}{216} \), we simply perform the operation in the numerator first: \[ 1 - 6 = -5 \] Now we can rewrite our fraction: \[ \frac{-5}{216} \] Since -5 and 216 have no common factors (other than 1), this fraction is already in its lowest terms. Thus, the final answer is: \[ \frac{-5}{216} \]