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Hypoglycemia is the most common serious side effect of insulin. It occurs in approximately \( 16 \% \) of Type I diabetic patie Consider a sample of 100 Type I diabetics taking insulin. Round to 4 decimal places (a) \( P \) (more than 13 having hypoglycemia \( )= \) (b) \( P(12 \) to 33 patients having hypoglycemia \( )= \)

Ask by Maxwell Gonzalez. in the United States
Mar 15,2025

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Answer

(a) The probability that more than 13 patients have hypoglycemia is approximately 0.7517. (b) The probability that between 12 and 33 patients have hypoglycemia is approximately 0.8907.

Solution

To solve this problem, we can model the number of Type I diabetics experiencing hypoglycemia as a binomial distribution. The parameters for this distribution are: - \( n = 100 \) (the number of trials, or patients) - \( p = 0.16 \) (the probability of success, or the probability that a patient experiences hypoglycemia) We can use the normal approximation to the binomial distribution since \( n \) is large. The mean \( \mu \) and standard deviation \( \sigma \) of the binomial distribution can be calculated as follows: \[ \mu = n \cdot p \] \[ \sigma = \sqrt{n \cdot p \cdot (1 - p)} \] Let's calculate \( \mu \) and \( \sigma \) first. Then we will use the normal approximation to find the probabilities for parts (a) and (b). ### Step 1: Calculate \( \mu \) and \( \sigma \) \[ \mu = 100 \cdot 0.16 \] \[ \sigma = \sqrt{100 \cdot 0.16 \cdot (1 - 0.16)} \] ### Step 2: Calculate the probabilities #### (a) \( P \) (more than 13 having hypoglycemia) To find \( P(X > 13) \), we can use the normal approximation: \[ P(X > 13) = 1 - P(X \leq 13) \] Using the continuity correction, we will calculate \( P(X \leq 13.5) \). #### (b) \( P(12 \) to 33 patients having hypoglycemia) To find \( P(12 \leq X \leq 33) \), we will calculate: \[ P(12 \leq X \leq 33) = P(X \leq 33) - P(X < 12) \] Using the continuity correction, we will calculate \( P(X \leq 33.5) \) and \( P(X < 11.5) \). Now, let's perform the calculations for \( \mu \) and \( \sigma \), and then find the probabilities. Calculate the value by following steps: - step0: Calculate: \(100\times 0.16\) - step1: Multiply the numbers: \(16\) Calculate or simplify the expression \( \sqrt(100 * 0.16 * (1 - 0.16)) \). Calculate the value by following steps: - step0: Calculate: \(\sqrt{100\times 0.16\left(1-0.16\right)}\) - step1: Subtract the numbers: \(\sqrt{100\times 0.16\times 0.84}\) - step2: Multiply the terms: \(\sqrt{13.44}\) - step3: Rewrite the expression: \(\sqrt{\frac{336}{25}}\) - step4: Use the properties of radicals: \(\frac{\sqrt{336}}{\sqrt{25}}\) - step5: Simplify the expression: \(\frac{4\sqrt{21}}{5}\) The calculations yield the following results: - Mean \( \mu = 16 \) - Standard deviation \( \sigma \approx 3.6661 \) ### Step 3: Calculate the probabilities #### (a) \( P(X > 13) \) Using the continuity correction, we need to find \( P(X \leq 13.5) \). To standardize this, we use the z-score formula: \[ z = \frac{x - \mu}{\sigma} \] For \( x = 13.5 \): \[ z = \frac{13.5 - 16}{3.6661} \] #### (b) \( P(12 \leq X \leq 33) \) We need to calculate: 1. \( P(X \leq 33.5) \) 2. \( P(X < 11.5) \) For \( x = 33.5 \): \[ z_{33.5} = \frac{33.5 - 16}{3.6661} \] For \( x = 11.5 \): \[ z_{11.5} = \frac{11.5 - 16}{3.6661} \] Now, let's calculate the z-scores for both parts. Calculate the value by following steps: - step0: Calculate: \(\frac{\left(33.5-16\right)}{3.6661}\) - step1: Remove the parentheses: \(\frac{33.5-16}{3.6661}\) - step2: Subtract the numbers: \(\frac{17.5}{3.6661}\) - step3: Convert the expressions: \(\frac{\frac{35}{2}}{\frac{36661}{10000}}\) - step4: Multiply by the reciprocal: \(\frac{35}{2}\times \frac{10000}{36661}\) - step5: Reduce the numbers: \(35\times \frac{5000}{36661}\) - step6: Multiply: \(\frac{35\times 5000}{36661}\) - step7: Multiply: \(\frac{175000}{36661}\) Calculate or simplify the expression \( (11.5 - 16) / 3.6661 \). Calculate the value by following steps: - step0: Calculate: \(\frac{\left(11.5-16\right)}{3.6661}\) - step1: Remove the parentheses: \(\frac{11.5-16}{3.6661}\) - step2: Subtract the numbers: \(\frac{-4.5}{3.6661}\) - step3: Convert the expressions: \(\frac{-\frac{9}{2}}{\frac{36661}{10000}}\) - step4: Multiply by the reciprocal: \(-\frac{9}{2}\times \frac{10000}{36661}\) - step5: Reduce the numbers: \(-9\times \frac{5000}{36661}\) - step6: Multiply: \(-\frac{9\times 5000}{36661}\) - step7: Multiply: \(-\frac{45000}{36661}\) Calculate or simplify the expression \( (13.5 - 16) / 3.6661 \). Calculate the value by following steps: - step0: Calculate: \(\frac{\left(13.5-16\right)}{3.6661}\) - step1: Remove the parentheses: \(\frac{13.5-16}{3.6661}\) - step2: Subtract the numbers: \(\frac{-2.5}{3.6661}\) - step3: Convert the expressions: \(\frac{-\frac{5}{2}}{\frac{36661}{10000}}\) - step4: Multiply by the reciprocal: \(-\frac{5}{2}\times \frac{10000}{36661}\) - step5: Reduce the numbers: \(-5\times \frac{5000}{36661}\) - step6: Multiply: \(-\frac{5\times 5000}{36661}\) - step7: Multiply: \(-\frac{25000}{36661}\) It seems that I attempted to use the wrong tool for finding the probabilities from the z-scores. Instead, I will provide the approximate probabilities based on standard normal distribution values. Using a standard normal distribution table or calculator: 1. **For \( z_{13.5} \approx -0.6819 \)**: - \( P(Z \leq -0.6819) \approx 0.2483 \) 2. **For \( z_{11.5} \approx -1.2275 \)**: - \( P(Z \leq -1.2275) \approx 0.1093 \) Now we can calculate the probabilities for parts (a) and (b): ### Final Calculations #### (a) \( P(X > 13) \) \[ P(X > 13) = 1 - P(X \leq 13.5) \approx 1 - 0.2483 = 0.7517 \] #### (b) \( P(12 \leq X \leq 33) \) \[ P(12 \leq X \leq 33) = P(X \leq 33.5) - P(X < 11.5) \approx 1 - 0.1093 = 0.8907 \] ### Summary of Results - (a) \( P(X > 13) \approx 0.7517 \) - (b) \( P(12 \leq X \leq 33) \approx 0.8907 \) Both probabilities are rounded to four decimal places.

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To solve this problem, we can use the binomial distribution, as we have a fixed number of trials (100 patients), two possible outcomes (hypoglycemia or no hypoglycemia), and a constant probability of success (16% or 0.16 for hypoglycemia). Let \( n = 100 \) (the number of trials), \( p = 0.16 \) (the probability of an event), and \( q = 1 - p = 0.84 \) (the probability of not having an event). We will use the normal approximation to the binomial distribution for calculations, since \( n \) is large. First, we need to determine the mean \( μ \) and standard deviation \( σ \): - Mean: \( μ = n \times p = 100 \times 0.16 = 16 \) - Standard deviation: \( σ = \sqrt{n \times p \times q} = \sqrt{100 \times 0.16 \times 0.84} \approx \sqrt{13.440} \approx 3.67 \) (a) To find \( P(X > 13) \), we need to convert it to a Z-score: - \( P(X > 13) = 1 - P(X \leq 13) \) - \( Z = \frac{X - μ}{σ} = \frac{13 - 16}{3.67} \approx -0.82 \) Now look up the Z-score of -0.82 in the standard normal distribution table (or use a calculator): - \( P(Z \leq -0.82) \approx 0.2061 \) Therefore: - \( P(X > 13) = 1 - 0.2061 = 0.7939 \) So, rounded to four decimal places, \( P(X > 13) \approx 0.7939 \). (b) For \( P(12 \leq X \leq 33) \): - Convert the boundaries to Z-scores: - For \( X = 12 \): - \( Z = \frac{12 - 16}{3.67} \approx -1.09 \) - \( P(Z \leq -1.09) \approx 0.1379 \) - For \( X = 33 \): - \( Z = \frac{33 - 16}{3.67} \approx 4.64 \) - \( P(Z \leq 4.64) \approx 1 \) (since 4.64 is very high) Now calculate \( P(12 \leq X \leq 33) \): - \( P(X \leq 33) - P(X \leq 12) \approx 1 - 0.1379 = 0.8621 \) So, rounded to four decimal places, \( P(12 \leq X \leq 33) \approx 0.8621 \). In summary: (a) \( P(X > 13) \approx 0.7939 \) (b) \( P(12 \leq X \leq 33) \approx 0.8621 \)

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