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What are the three types of mutations and describe what happens in each? a.

Ask by Nguyen Harmon. in the United States
Mar 11,2025

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There are three types of mutations: 1. **Silent Mutation**: Changes in DNA that don't affect the protein. 2. **Missense Mutation**: Replaces one amino acid with another in the protein. 3. **Nonsense Mutation**: Changes a codon to a stop signal, making the protein shorter.

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1. **Silent Mutation** A silent mutation is a change in the nucleotide sequence that does not change the amino acid encoded by the codon. For example, if a codon \( UCU \) (coding for serine) is mutated to \( UCC \) (which also codes for serine), the protein’s amino acid sequence remains unchanged, and hence the mutation is “silent.” 2. **Missense Mutation** A missense mutation is a point mutation in which one nucleotide is changed, resulting in the substitution of one amino acid for another in the protein. For instance, if the codon \( GAA \) (coding for glutamic acid) is altered to \( GUA \) (coding for valine), the protein now has valine in place of glutamic acid. This single change can affect the protein’s structure and function. 3. **Nonsense Mutation** A nonsense mutation is a point mutation in which a codon that formerly coded for an amino acid is changed into a stop codon. This results in premature termination of protein synthesis. For example, if the codon \( UAU \) (coding for tyrosine) mutates to \( UAA \) (a stop codon), the polypeptide chain is truncated, often rendering the protein nonfunctional.

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Mutations come in three fascinating forms! First up, we have **point mutations**, where a single nucleotide is altered. This can lead to a change in an amino acid in a protein, which might be harmless or cause a cascade of effects—think of it as a single typo in a manuscript. Next, there are **insertion mutations**, where extra nucleotides are added into the DNA sequence. This can shift the entire reading frame, similar to adding extra letters into a sentence that can make it nonsensical. Lastly, we have **deletion mutations**, which involve losing nucleotides from the DNA. Like erasing words from a book, this can have dramatic results on a protein’s function, possibly resulting in a nonfunctional or harmful protein! Now, why do these mutations matter? They’re crucial in the realm of evolution, my friend! Mutations introduce genetic diversity, providing raw material for natural selection to act upon. For instance, a beneficial mutation can help an organism adapt to its environment, like a polar bear's white fur offering camouflage in the snow. This evolutionary dance not only shapes species but gives rise to new ones over long periods, making mutations the spotlight feature in the grand theater of life!

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