Pregunta
- Mary, a patient in a nursing home, has been diagnosed with a urinary tract
infection (UTI). Her physician prescribes Cipro, a popular antibiotic that is
very effective in controlling UTIs and has been effective previously when
treating these infections in Mary. However, this time, the antibiotic has no
effect and the infection persists.
a. Propose an explanation for the difference in Mary’s response to the
antibiotic from previous treatments.
b. If you were Mary’s physician, how would you proceed with her treatment?
infection (UTI). Her physician prescribes Cipro, a popular antibiotic that is
very effective in controlling UTIs and has been effective previously when
treating these infections in Mary. However, this time, the antibiotic has no
effect and the infection persists.
a. Propose an explanation for the difference in Mary’s response to the
antibiotic from previous treatments.
b. If you were Mary’s physician, how would you proceed with her treatment?
Ask by Coles Warner. in the United States
Mar 12,2025
Solución de inteligencia artificial de Upstudy
Respuesta verificada por el tutor
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(a) Explanation for Difference in Response
Mary’s antibiotic didn’t work this time because the bacteria causing her UTI may have become resistant to Cipro. This means the bacteria have developed ways to fight the antibiotic, making it less effective.
(b) Proceeding with Treatment
If I were Mary’s doctor, I would:
-
Get a Culture and Sensitivity Test:
Find out which bacteria is causing the UTI and which antibiotics it responds to. -
Check Medical History:
Look for any factors that might have led to antibiotic resistance. -
Change the Antibiotic:
Prescribe a different antibiotic that the bacteria are sensitive to based on the test results. -
Monitor Mary’s Health:
Keep an eye on how Mary responds to the new treatment and adjust as needed. -
Prevent Spread of Bacteria:
Make sure Mary’s environment is clean to stop the bacteria from spreading.
By doing these steps, Mary can get the right treatment to fight her UTI effectively.
Solución
(a) Explanation for Difference in Response
Mary’s current lack of improvement with Cipro could be due to the development of bacterial resistance. Over time, bacteria may acquire mutations or resistance mechanisms such as enzymes that degrade the antibiotic, altered target sites, or increased efflux that pump the antibiotic out of the cell. This resistance diminishes the effectiveness of
(b) Proceeding with Treatment
If I were Mary’s physician, I would take the following steps:
-
Obtain a Culture and Sensitivity Test:
Assess which bacteria is causing the UTI and determine its antibiotic sensitivity profile. This helps identify whether resistance tois present and which alternative antibiotic might be effective. -
Review Previous Medical History and Medications:
Check for any factors (such as recent antibiotic use or drug interactions) that could have contributed to resistance or impacted the absorption and effectiveness of. -
Adjust Antibiotic Therapy Based on Test Results:
Once the culture and sensitivity results are available, prescribe an alternative antibiotic that the bacteria appear to be sensitive to. This may involve switching to another class of antibiotics. -
Monitor Mary’s Response:
Regularly assess Mary’s clinical response to the new antibiotic regimen and adjust the treatment as necessary. -
Consider Infection Control Measures:
Implement measures to prevent further spread of resistant bacteria in the nursing home environment, which may include additional screening or isolation procedures if warranted.
By following these steps, the treatment is personalized based on Mary’s current infection profile, increasing the likelihood of a successful outcome.
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Simplifique esta solución Bonus Knowledge
One possible explanation for the difference in Mary’s response to Cipro this time could be the development of antibiotic resistance. Bacteria can mutate over time or acquire resistance genes, rendering previously effective antibiotics ineffective. If Mary has had multiple courses of Cipro or other similar antibiotics, the bacteria causing her UTI may have adapted and become resistant to the drug, necessitating a change in her treatment approach.
As Mary’s physician, I would first consider conducting a urine culture and sensitivity test to identify the specific bacteria causing the infection and to determine which antibiotics it is sensitive to. Based on the results, I would select an appropriate alternative antibiotic that hasn’t been used previously on Mary or consider using combination therapy to overcome the resistance. Additionally, discussing preventive measures to reduce future UTIs would be crucial for her long-term health.
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