What is your prediction for this experiment? A. A reaction will take place if water is present. B. Any combination of chemicals that contains an enzyme will exhibit a reaction. C. Only specific combinations of an enzyme and substrate will exhibit a reaction.

1. **Understanding the experiment** Enzymes are biological catalysts that speed up specific reactions in living systems. They have an active site where only a particular substrate binds. 2. **Reviewing the options** - **Option A:** Involves the presence of water, although water is a solvent and not directly responsible for the enzyme-substrate reaction. - **Option B:** States that any combination of chemicals with an enzyme will react, which contradicts the specificity enzyme reactions require. - **Option C:** Specifies that only the correct combination of an enzyme and its specific substrate will result in a reaction, which aligns with the fundamental property of enzymes. 3. **Conclusion** Since enzymes require a specific substrate to bind to their active site, the correct prediction is that a reaction will only occur when the proper enzyme-substrate pairing is present. Thus, the correct answer is: \( \textbf{C. Only specific combinations of an enzyme and substrate will exhibit a reaction.} \)