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How do the kidneys function in the homeostatic regulation of pH of body fluids? Multiple Choice The kidneys manufacture hydrochloric acid and sodium hydroxide depending upon the pH needs of the body. The kidneys regulate pH through control of the amount of oxygen and carbon dioxide in the bloodstream and absorption of hydrogens ions and bicarbonate as needed. The kidneys regulate pH of body fluids by controlling how much glucose and amino acids are present in body fluids. The The

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Mar 09,2025

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The kidneys regulate pH by controlling oxygen and carbon dioxide levels and by absorbing or releasing hydrogen ions and bicarbonate as needed.

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To understand how the kidneys function in the homeostatic regulation of pH of body fluids, let's analyze the options provided: 1. **The kidneys manufacture hydrochloric acid and sodium hydroxide depending upon the pH needs of the body.** - This statement is incorrect. The kidneys do not manufacture these acids or bases directly. Instead, they regulate pH through other mechanisms. 2. **The kidneys regulate pH through control of the amount of oxygen and carbon dioxide in the bloodstream and absorption of hydrogen ions and bicarbonate as needed.** - This statement is correct. The kidneys help maintain acid-base balance by excreting hydrogen ions and reabsorbing bicarbonate from urine. They also influence the levels of carbon dioxide indirectly through their effects on respiration. 3. **The kidneys regulate pH of body fluids by controlling how much glucose and amino acids are present in body fluids.** - This statement is incorrect. While the kidneys do filter glucose and amino acids, their primary role in pH regulation is not through these substances. Based on this analysis, the correct answer is: **The kidneys regulate pH through control of the amount of oxygen and carbon dioxide in the bloodstream and absorption of hydrogen ions and bicarbonate as needed.**

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The Deep Dive

The kidneys play a crucial role in maintaining the acid-base balance of the body by regulating the concentration of hydrogen ions (H+) and bicarbonate (HCO3-) in the blood. When the blood becomes too acidic, the kidneys excrete more H+ ions and reabsorb more bicarbonate, which helps to raise the pH back to a healthy level. Conversely, when the blood is too alkaline, the kidneys can reduce bicarbonate reabsorption and retain more H+ ions, thereby lowering the pH. In real-world scenarios, this regulation is vital during activities that produce lactic acid, like intense exercise, or in conditions like respiratory distress that can affect CO2 levels. For instance, if you're working out hard, your body generates more lactic acid, and the kidneys kick in to balance the pH, making sure you remain functional. This homeostatic balancing act is critical not just for performance but also for overall health!

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