A doctor prescribed Xanax (alprazolam) \( 1.5 \mathrm{mg} / \mathrm{m}^{2} \) by mouth (PO) per day. This patient has a Body Surface Area (BSA) of \( 1.25 \mathrm{~m}^{2} \). How many 0.75 mg scored tablets of this anti- anxiety drug will you administer to the patient who suffers from panic attack per day?
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The Deep Dive
To determine the daily dosage for the patient, first, you need to calculate the total prescribed dose based on the patient's Body Surface Area (BSA). The doctor prescribed \( 1.5 \mathrm{mg/m}^2 \) and the patient's BSA is \( 1.25 \mathrm{m}^2 \). Total dose = \( 1.5 \mathrm{mg/m}^2 \times 1.25 \mathrm{m}^2 = 1.875 \mathrm{mg} \) per day. Next, you need to figure out how many 0.75 mg scored tablets are needed to meet this total dosage. Dividing the total daily dose by the strength of each tablet: \( \frac{1.875 \mathrm{mg}}{0.75 \mathrm{mg/tablet}} = 2.5 \) tablets. Since you're working with scored tablets, you can administer 2 scored tablets (1.5 mg) plus half of a tablet (0.375 mg) to reach the total of 1.875 mg. So, the patient should take 2.5 tablets of Xanax per day.
